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Section XVI

Standard operating procedures (SOP) and Fact Sheets are intended to provide you with general guidance on how to safely work with a specific class of chemicals or type of hazard. While SOPs & Fact Sheets provide only general guidance, observance of all the safety practices listed in them is mandatory. If compliance with all the requirements of a specific standard operating procedure is not possible, the principal investigator must develop a written procedure that will be used in its place. This alternate procedure must provide the same level of protection as the SOP it replaces. The Office of Environmental Health and Radiation Safety is available to provide guidance during the development of alternate procedures.


How to use SOPs

The Standard Operating Procedures in the following section are written for situations where the quantity of chemical that is handled is large enough to pose a risk to the worker. Obviously if you are working with microliter quantities of flammable liquid you do not need to work in a fume hood. Similarly, microgram quantities of most acutely toxic materials can be safely handled on the bench top rather than in a fume hood or glove box. The selection of the control mechanism (i.e., fume hood, biosafety cabinet, glove box) must be based on the quantity and the particular hazard of the chemical you work with. Questions concerning proper handling procedures should be directed to your Principal Investigator or to Environmental Health and Radiation Safety.


Hazard Control Plans

The SOPs and Fact Sheets in the Chemical Hygiene Plan provide guidance on broad categories of hazards. A Hazard Control Plan (HCP), however, is a lab-specific and/or task-specific SOP that describes the hazards and controls for a particular procedure you will perform in your lab.  Anyone can complete the HCP, but the completed plan must be reviewed by the supervising PI.

An HCP should be written:

  • Whenever a new hazard type is introduced in your work 
  • When the hazards of a procedure are unknown
  • When the hazards of a task are considered particularly high.  
  • Before the hazardous task is performed for the first time.

Hazard Control Plan Template

INSTRUCTIONS:  Click on the link and save a copy of the Word document to your computer before completing the form or your changes may be lost.

Email your completed HCP to EHRS (  EHRS will upload the document to the documents section of your lab's BioRAFT profile.